Our Evolving Understanding of What Causes Migraine


Key Questions
  • How is a systemic disease defined, and is migraine considered one?
  • What’s happening in the brain and body when a migraine attack occurs?
  • What is known about the causes of migraine and its relationship to other conditions (comorbidities)?
  • What role do genes and environmental factors play in migraine disease?
  • Is there an underlying “root cause” of migraine?
  • What is the difference between a cause and a trigger?
  • Can treatment of comorbid conditions lead to improvements in migraine symptoms?
  • How might a systemic approach to understanding migraine disease influence treatment approaches?
  • What are the potential long-term effects of migraine?
  • What priorities should guide the next generation of migraine research?
Vince Martin

Vince Martin, MD, AQH

Director
Headache & Facial Pain Center

Vincent Martin is the director of the Headache and Facial Pain Center at the University of Cincinnati Gardner Neuroscience Institute. He has been a professor of clinical medicine in the Division of General Internal Medicine at the University of Cincinnati College of Medicine since 2004.

Dr. Martin is immediate past president of the National Headache Foundation and a fellow of the American Headache Society and the American College of Physicians.


Interviews from Vince Martin, MD, FAHS, AQH

The Gut Factor: Exploring the Role of Digestive Health in Migraine
Making the Most Out of Your Doctor’s Appointment
Ehlers-Danlos, Connective Tissue Disorders & Migraine
Migraine Diets and Food Triggers
Surviving Weather-Related Migraine

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Related Talks for: Day 5 (2026)

Living With Migraine Through Times of Grief & Loss

Dawn C. Buse, PhD

Mast Cells: A Link Between Migraine, POTS & EDS?

Jennifer Robblee, MD, MSc

Understanding Migraine Drug Side Effects

Teshamae Monteith, MD, FAHS, FAAN

The Migraine Trust is dedicated to helping people affected by migraine. We are the only UK migraine charity providing information and support, campaigning for awareness and change, and funding and promoting research.

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