New Daily Persistent Headache: Causes, Symptoms & Treatment

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Key Questions
  • What is new daily persistent headache (NDPH)?
  • What research is in progress to better understand NDPH?
  • Why are people with NDPH able to accurately remember the day it began?
  • How is chronic migraine different from NDPH? Can one person have both conditions?
  • How long does a headache need to last to meet the definition of NDPH?
  • Can NDPH result from another underlying illness?
  • What conditions can be misdiagnosed as NDPH?
  • What is a diagnosis of exclusion?
  • How is NDPH diagnosed and by what type of health care provider?
  • Who does NDPH most typically affect?
  • What is hemicrania continua and how is it different from NDPH?
  • How is NDPH treated, including nonmedicinal approaches?
  • How effective are the treatments for NDPH?
  • How are the CGRP monoclonal antibodies and Botox used in NDPH?
  • Can NDPH go into remission?
  • What can we do if we feel like we’ve tried everything for our headaches and nothing has worked?
  • What is the American Registry for Migraine Research?
  • How can we support migraine research?
  • Why should we remain hopeful for the treatment of NDPH?
Interview Notes

Find more about David Dodick, MD and his work here:

Treatments Mentioned
  • Biofeedback
  • Botulinum toxin
  • CGRP monoclonal antibodies
  • Cognitive behavioral therapy
  • Dietary modifications
  • Exercise
  • Mindfulness
  • Neuromodulation devices
  • Relaxation therapy

Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.

David Dodick, MD

Professor (Emeritus)
Mayo Clinic, Arizona

David Dodick, M.D., FAAN, is a professor of neurology at the Mayo Clinic College of Medicine and Science in Scottsdale, Arizona. He is the director of the headache program and the sports neurology and concussion program at Mayo Clinic in Arizona. He is an adjunct professor in the department of neurosciences, Norwegian University of Science and Technology. Dr. Dodick is board certified by the Royal College of Physicians and Surgeons of Canada and the American Board of Psychiatry and Neurology (ABPN). He also holds United Council for Neurologic Subspecialties certification in headache medicine and ABPN certification in vascular neurology.

Dr. Dodick has authored more than 380 peer-reviewed publications and authored/edited 10 books. He is the chair of the American Migraine Foundation, chair of the American Academy of Neurology (AAN) Annual Program Concussion Committee, co-director of the American Registry of Migraine Research, chair of the International Registry for Migraine Research, chair of the International Headache Society Global Patient Advocacy Coalition, co-director of the Annual AAN Sports Concussion Conference, president-elect of the International Concussion Society, immediate past-president of the International Headache Society, former editor-in-chief of Cephalalgia, and past-president of the American Headache Society.

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The Association of Migraine Disorders (AMD) is devoted to expanding the understanding of migraine disease and its true scope. Migraine is a full body condition with a broad spectrum of symptoms, AMD is focused on including many medical specialties in the management of this disease.

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