Inflammation Control as Migraine Control

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Key Questions
  • What is inflammation?
  • Does inflammation serve a purpose?
  • Is inflammation as important as it’s made out to be in health communities?
  • Is there a way to measure inflammation in the body?
  • Are there known inflammatory markers in people with migraine?
  • Does inflammation lead to migraine, or does migraine lead to inflammation?
  • Does uncontrolled chronic migraine cause chronic inflammation, leading to other pain conditions?
  • What does the gut have to do with inflammation?
  • Are anti-inflammatory medications the best antidote to inflammation?
  • What are some other ways to fight inflammation?
  • Can diet influence inflammation?
  • What do omega-3s and omega-6s have to do with inflammation and migraine?
  • Are there any supplements that can help inflammation?
  • What is the relationship between inflammation and some conditions that are comorbid with migraine, such as depression, anxiety, and sleep disorders?
  • Is exercise beneficial or harmful for inflammation?
Interview Notes

Find out more about Gretchen Tietjen, MD and her work here:

Treatments Mentioned
  • Acetaminophen
  • CGRP antagonists
  • DHE, intranasally
  • Diet high in omega-3’s, low in omega-6’s
  • Ditans
  • Exercise
  • Gepants
  • Meditation
  • Neuromodulatory devices
  • NSAIDs
  • Sleep
  • Steroids
  • Tai chi
  • Triptans
  • Yoga

Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.

Gretchen E. Tietjen, MD

Professor Emerita of Neurology
University of Toledo

Dr. Gretchen E. Tietjen is a graduate of the University of Michigan Medical School and its neurology residency program. She is a Distinguished University Professor Emerita of neurology at the University of Toledo, where she founded the Department of Neurology in 2000 and led as chair for the next 20 years.

Specializing in headache medicine and vascular neurology, she also directed the Stroke Center for 15 years and the Headache Treatment and Research Center for over two decades. Her research focuses on the relationship between migraine and stroke, including the investigation of the vascular biology in migraine, the association of childhood maltreatment and migraine, and the effects of early life stress on vascular and brain biology in a rodent model.

Dr. Tietjen has published over 160 peer-reviewed papers, book chapters, reviews, and editorials. Her research has garnered national awards, including the Stroke Innovation Award from the journal Stroke and the Association of Migraine Disorders Innovation Award, as well as the American Headache Society’s Seymour Solomon Lecture Award, the Harold G. Wolff Lecture Award, the John R. Graham Lecture Award, the Women’s Health Research Lecture Award, and the 2022 Lifetime Achievement Award from the AHS.

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