Is Migraine Linked With Cognitive Decline or Dementia?

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Key Questions
  • What is the definition of a risk factor?
  • What is dementia?
  • What causes dementia?
  • What has the research found regarding links between migraine and dementia?
  • Why is it difficult to research this topic?
  • Can diet be a factor in migraine and dementia?
  • What are some examples of cerebrovascular diseases and their links to migraine and dementia?
  • What is glymphatic drainage? How might it be a component of migraine and a potential pathway to dementia?
  • Pain, stress, and inflammation are part of migraine. Are they also risk factors for dementia?
  • Is there any evidence that migraine causes cognitive decline?
  • Is it natural for everyone to experience cognitive decline as we age?
  • Can cognitive decline be accelerated by medications?
  • Can fear and anxiety exacerbate or accelerate cognitive decline?
Interview Notes
Treatments Mentioned
  • Amitriptyline
  • Exercise
  • Mediterranean diet
  • Nortriptyline
  • Omega-3 fatty acids
  • Sleep
  • Topiramate (Topamax)

Please note: The Migraine World Summit’s aim is to bring you a variety of perspectives and expertise, independent of bias or judgment. Alternative theories presented in this video have not been medically reviewed. Views expressed in this interview do not necessarily represent the views of the Migraine World Summit. Please always consult your health care professional and do your own research before making changes to your treatment plan.


Richard B. Lipton, MD

Professor of Neurology & Director of the Montefiore Headache Center, and Director of the Division of Cognitive Aging and Dementia
Albert Einstein College of Medicine

Dr. Richard B. Lipton is an expert in headache and migraine management, as well as cognitive aging and dementia. He serves as the director of the Montefiore Headache Center and holds the prestigious Edwin S. Lowe chair in neurology at Albert Einstein University in New York. Internationally acclaimed for his contributions to headache diagnosis, classification, epidemiology, and treatment, Dr. Lipton has an impressive bibliography with 11 books and over 1,000 articles in indexed journals. His textbook, Headache in Clinical Practice, earned him the Medical Book Award from the British Medical Association.

He is past president of the American Headache Society (AHS), and is an associate editor for Cephalalgia: An International Journal of Headache. Additionally, he contributes to several other editorial boards, including for Neurology. His outstanding research has been recognized six times with the Harold G. Wolff Lecture Award from the AHS. Beyond neurology, Dr. Lipton is also a professor in psychiatry, behavioral sciences, epidemiology, and population health at the Albert Einstein College of Medicine.

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